Mono?Gold(I)?Catalyzed Enantioselective Intermolecular Reaction of Ynones with Styrenes: Tandem <i>Diels–Alder</i> and Ene Sequence
نویسندگان
چکیده
Gold-catalyzed intermolecular reaction leading to dihydronaphthalene derivatives in one pot from two equivalents of ynones with respect styrene is uncovered. The [4+2] Diels–Alder cycloaddition and styrenes catalyzed by a mono-gold(I) complex the conjugated acid provide an unstable 3,8a-dihydronaphthalene subsequently undergo ene-type ?-activated ynone afford multi-component coupling products. Linear relationships between chiral ligand-gold complexes products proves mono-gold catalysis that triggers asymmetric tandem ene sequence.
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ژورنال
عنوان ژورنال: Helvetica Chimica Acta
سال: 2021
ISSN: ['1522-2675', '0018-019X']
DOI: https://doi.org/10.1002/hlca.202000198